What physical indicator may suggest an individual is impaired by alcohol or drugs?

Cool, clammy skin is a significant physical indicator that may suggest an individual is impaired by alcohol or drugs. When someone is under the influence, their body's ability to regulate temperature and moisture can be affected. This often results in changes in skin temperature and moisture levels. Cool and clammy skin may indicate that a person is experiencing a negative reaction to substances, which can be due to factors such as dehydration or changes in circulation.

In contrast, other options do not carry the same level of association with impairment. Brightly colored clothing does not indicate someone's physical or mental state and could be a simple matter of personal style. A cheerful demeanor, while sometimes seen in individuals under the influence, does not consistently indicate impairment. Similarly, constant laughter might occur for various reasons but is not a reliable or definitive sign of alcohol or drug use. Therefore, the presence of cool, clammy skin stands out as a more objective and observable indicator of potential impairment.